James F Dyer

James F. Dyer, photograph ca. 1888, Hill County, TX
 



Analysis of FGC12290 SNP

SUMMARY OF YSNP (May, 2016)

 

Classification of Branch: Medium Branch- son of FGC5660.

Known sons: FGC12296 is the son of FGC12290.

Estimated Breadth of branch (speculative estimate of positive submissions) = around 24 submissions are known but scope is probably larger.

Scope of Testing within Signature: There is substantial testing for the three YSNPs in this branch. There are four NGS tests. However, results are not complete for 156885 - this tester probably needs to send Dennis Wright the BAM files for analysis. Another NGS test is only 37 markers and could not be used since haplotree analysis requires 67 markers.

Dominant Surnames: McCraw variations (14), Thomas (3) Littrell variations (3), Wright (2), Howell (1), Peppers (1), Spears (1) and Milam (1) - many more could be added once the true scope of branch becomes better known.

Date that branch was discovered: Unknown.

Source of Branch discovery: Two FTDNA Big Y tests (25505 and 69433).

Number of Negative Broad Tests: Around 45 NGS tests and 30 more via packs & panels.

Number of Negative Tests within Signature: One submission has tested negative for FGC12294, so this is a potential new branch once a second person tests positive.

Pending Tests (within signature): None known.

 

ANALYSIS OF CURRENT FGC12290 HAPLOTREE

I manually separated around 113 L226 submissions combined with 22 known YSNP results and used the SAPP tool to generate a chart which shows FGC12290 as a much broader scope YSNP than manual analysis supports. However, SAPP appears to be accurate upon inspection for those submissions when compared to manual analysis. This branch of L226 has several issues preventing the complete descendant chart of FGC12290:

1) There are three major signatures associated with FGC12290. The largest signature was six off modal mutations from L226 but only two Wright submissions matched this signature very well. This signature defines a potential new FGC12294 branch since the other two branches has tesed negative for FGC12294. The second signature consists of three mutations and defines the branch FGC12296 and includes six submission (three have the Thomas surname). The third signature only includes two mutations but is obviously a clean signature as it includes twelve McCraw variations and three Littrell variation. Only one other submission, Milam, belongs to the branches associated of this signature. This branch represents the FGC12290+ FGC12296- branch.

2) The current limit of around 110 submissions limits the accuracy of the desendant chart for this particular L226 branch. As more submissions are included in the SAPP analysis and more YSNPs are tested, a few more submissions may be added to the FGC12290 branch over time.

3) The three signatures associated with the FGC12290 and its descendant branches was able 22 good testing candidates.

 

OTHER FUTURE YSNP TESTING

No pending tests are known.

 

FGC12290 Haplotree

The link to the haplotree chart is the best way to look at the evolution of the FGC12290 haplotree. It is visually much easier to follow than spreadsheets and is very close to a genealogist descendant tree charts that genealogists already are well trained in analyzing:

 

Haplotree of FGC12290

 

Testing Candidate Recommendations

This summary will attempt to priortize testing and explain why each test is beneficial to the the verification of the FGC12290 branches and determining the scope of these branches.

 

Here are the priorities for testing:

1) The scope of FGC12290 is fairly well known but its scope could increase substantially with more submissions allowed by SAPP and more genetic information as input to SAPP (new YSNP testing and new 67 marker YSTR submissions).

2) It is recommended that all current submissions that are predicted positive for FGC12290 branches should test only FGC12290 branches for $17.50 from YSEQ.

3) There are currently many predicted FGC12290 positive testing candidates:

For the signature associated with FGC12296:

124291 Wright - test FGC12294 and FGC12296

For the signature associated with FGC12296+ and FGC12294-

96494 Peppers - test only FGC12296 and FGC12294.
281966 Spears - test all three branches (90, 96 and 94)
262476 Howell - test all three branches (90, 96 and 94)
N24190 McGrath - test all three branches (90, 96 and 94)
136354 Thomas - test all three branches (90, 96 and 94)
B11123 Thomas - test all three branches (90, 96 and 94)

For the signature associated with FGC12290+ and FGC12296-

235830 Lutre - test only FGC12290 and FGC12296
146271 Littrell - test only FGC12290 and FGC12296
58423 Littrell - test only FGC12290 and FGC12296
139659 Milam - test only FGC12290 and FGC12296

From the large McCraw variants - 3 or 4 more should
test FGC12290 and FGC12296 only:

197170, 68723, 212335, 187858, 112897, 139659,
126287, 319285, 349546, 162666, 256601 and 125874.

4) Once these testing candidates are confirmed for the relevant branches under FGC12290, testing is recommended for the private YSNPs associated with the NGS submission whose signature matches (in the same branch). Future updates of this section will recommend further testing of private YSNPs for each signature.